Detalhe da pesquisa
1.
Biophysical and computational fragment-based approaches to targeting protein-protein interactions: applications in structure-guided drug discovery.
Q Rev Biophys
; 45(4): 383-426, 2012 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-22971516
2.
Synthesis and structure-activity relationship of aminopyrimidine IKK2 inhibitors.
Bioorg Med Chem Lett
; 18(12): 3622-7, 2008 Jun 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-18501602
3.
Arpeggio: A Web Server for Calculating and Visualising Interatomic Interactions in Protein Structures.
J Mol Biol
; 429(3): 365-371, 2017 02 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-27964945
4.
Identifying Interactions that Determine Fragment Binding at Protein Hotspots.
J Med Chem
; 59(9): 4314-25, 2016 05 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-27043011
5.
What can we learn from the evolution of protein-ligand interactions to aid the design of new therapeutics?
PLoS One
; 7(12): e51742, 2012.
Artigo
em Inglês
| MEDLINE | ID: mdl-23240060
6.
Extent of enthalpy-entropy compensation in protein-ligand interactions.
Protein Sci
; 20(9): 1607-18, 2011 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-21739503
7.
Atomic interactions and profile of small molecules disrupting protein-protein interfaces: the TIMBAL database.
Chem Biol Drug Des
; 74(5): 457-67, 2009 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-19811506
8.
A consensus neural network-based technique for discriminating soluble and poorly soluble compounds.
J Chem Inf Comput Sci
; 43(2): 674-9, 2003.
Artigo
em Inglês
| MEDLINE | ID: mdl-12653537
9.
A novel series of potent and selective IKK2 inhibitors.
Bioorg Med Chem Lett
; 14(2): 409-12, 2004 Jan 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-14698170
10.
Selecting screening candidates for kinase and G protein-coupled receptor targets using neural networks.
J Chem Inf Comput Sci
; 42(5): 1256-62, 2002.
Artigo
em Inglês
| MEDLINE | ID: mdl-12377017
11.
Database searching for thymidine and thymidylate kinase inhibitors using three-dimensional structure-based methods.
J Enzyme Inhib Med Chem
; 17(3): 167-74, 2002 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-12443042